Industry

See every batch ripple before release slips.

RippleFlo simulates pharma process manufacturing — API synthesis, hold times, blending, fill-finish, and release windows — with DES-powered ripple tracing and audit-grade replay. Also built for aerospace, process, discrete, and critical manufacturing.

10×
faster batch what-if cycles
30%
less schedule rework
100%
release traceability
RippleFlo digital twin factory floor with simulation overlay
Ripple Alert
Reactor R2 queue · 18h
3 batches impacted · BX-77 slip 6h
On-time projection
94.2%
+6.1 vs baseline
Production Timeline · 14-day
Planned Actual Downtime
CNC1
Lathe
QC
Pack

Starting with pharma — extending to every critical manufacturing vertical

Pharma & Biotech
API Manufacturing
Fill-Finish
Process Batch
Critical Manufacturing
Aerospace

Today's planning stack lies to you — in every industry.

Spreadsheets hide queue effects

One delay compounds across shared stations — whether it's a CNC queue, reactor campaign, or fill line.

ERP assumes a perfect world

No breakdowns, no alternate routes, no shift calendar reality — across discrete and process lines alike.

Firefighting is expensive

Overtime, expedites, and lost credibility with customers, regulators, and program offices.

Critical mfg needs evidence

In regulated environments, you can't just reschedule — you need traceability, replay, and defensible decisions.

Pharma process manufacturing needs foresight — not another ERP schedule.

ERP records what happened on the batch record. RippleFlo simulates what will happen across API synthesis, hold times, blending, fill-finish, and release windows — before QA finds a deviation.

Exploring another industry? Use the selector above — Aerospace, Process, Discrete, Medical, and Critical Manufacturing each have dedicated pages.

ERP / MES in pharma

Plans batches. Can't model the process.

ERP handles orders, BOMs, inventory, and batch records. It assumes average cycle times and dedicated equipment — but pharma is campaigns, holds, shared reactors, and release windows.

  • Schedules batches on average lead times — not reactor queues or hold-time chains
  • Cannot model campaign overlap when two products share validated equipment
  • Batch record deviations discovered at QA sign-off, not days earlier
  • Changing a release date means re-planning across planning, QA, and ops manually
RippleFlo for pharma

Simulates the batch journey.

A discrete-event digital twin of your pharma line. Batches flow event by event through reactors, holds, QC gates, and fill-finish — with release risk scored before the window closes.

  • Simulates API synthesis → hold → blending → fill-finish as discrete events
  • Scores every batch on track, at risk, or critical before release window slips
  • Traces reactor delays through hold, QC IPC, and fill-finish in one ripple map
  • Pre-commit blast preview shows which lots shift before QA publishes a change

Pharma process manufacturing — ERP vs RippleFlo

DimensionERP / MESRippleFlo
Batch schedulingFixed lead times per SKUCampaign windows with queue & hold modeling
Equipment sharingAssumes dedicated linesValidated train contention & overlap detection
Hold timesStatic offset in planDynamic hold chains that ripple downstream
Release riskDiscovered at sign-offAmber/red scoring days before deviation
Lot splittingManual spreadsheet mathMin/max batch sizes simulated in DES
Equipment failureLogged after production stopsMTBF/MTTR injected — measure batch slip
Audit trailReconstruct from batch recordsDeterministic replay + commitment diff
What-if costChange the real campaignRe-run the model — zero shop-floor risk

Watch a pharma campaign ripple through the line.

Reactor R2 builds queue. Hold times extend. Fill-finish slips. Release windows turn amber — all visible before a batch record changes.

Campaign BX-77 · API → Fill-Finish· DES tick 18:42:07
API Prep
45m/batch · buf 2
In process
Reactor R2
18h/batch · buf 4
Queue build
Hold Tank
6h hold · buf 3
Ripple slip
Blending
2h/batch · buf 2
In process
QC IPC
90m/batch · buf 1
In process
Fill-Finish
4h/batch · buf 2
In process
QC Release
24h/batch · buf 5
On hold
Batch Release
Window Sep 16
At risk
Ripple trace · Reactor R2
18h queue · hold extended
BX-77 slip +6h · Fill-Finish Sep 14 → Sep 16
Release risk
At risk
2 batches in QA hold · 1 past window
Campaign WIP
5 batches
+2 vs plan
Reactor util
94%
bottleneck
Hold queue
18h
+6h ripple
Release window
Sep 16
2d slip risk
Batch slip · Reactor R2 delay
BX-74
+0h
BX-75
+2h
BX-76
+4h
BX-77
+6h
BX-78
+8h

How RippleFlo solves what ERP cannot in pharma.

Process manufacturing in regulated environments needs simulation-backed decisions — not spreadsheet hope.

Campaign overlap detection

See when Batch BX-77 and BX-78 compete for Reactor R2 before either misses a release window.

Hold-time ripple chains

A 6-hour hold extension traces the slip through fill-finish and QC release — not just one operation.

QA-ready risk scoring

Flag batches at risk before deviation paperwork. Planning and QA see the same amber alert.

Validated alternate routes

When Reactor R2 is down, DES routes through the next qualified train.

Release window defense

Pegging tree from customer PO → batch → operation → root cause for review or regulator.

Audit-grade replay

Re-run any historical campaign scenario with identical inputs.

Reactor R2 down 18 hours. Five batches. Five different release stories.

ERP reschedules on averages. RippleFlo measures slip per batch against its own release window — BX-77 slips 6 hours while BX-75 only slips 2 because its hold cleared before the queue peaked.

  • Per-batch slip with attribution (% Reactor R2 vs downstream hold)
  • Stage-to-stage trace: if hold extends, when does fill-finish move?
  • Pre-commit preview — see which release windows shift before QA signs off
Demo a pharma campaign
pegging.trace · BX-77
PO #48201 · Customer ACME-Bio
└─ Batch BX-77 · Release Sep 16
└─ Lot 2208-B · 6h slip
└─ Op 020 · Reactor R2 queue 18h
└─ Hold extended +6h
└─ Reroute → Reactor R3 (validated)
└─ Audit entry #91244 ✓

Explore other industries.

Pharma is our default focus — switch anytime using the industry selector above. Each vertical has its own ERP comparison, process animation, and use cases.

Default

Pharma & biotech

Batch release risk scoring, campaign scheduling, validated equipment trains, and hold-time modeling — so QA sees amber alerts before deviations.

  • Batch & lot splitting
  • Release window scoring
  • Regulator-ready audit trail
Currently viewing
Core focus

Critical manufacturing

Audit-grade traceability, pre-commit blast preview, deterministic replay, and commitment pegging for environments where every schedule change must be defensible.

  • Simulation history archive
  • Commitment diff on publish
  • War Room crisis coordination
Explore Critical
Vertical

Aerospace & defense

Contractual delivery promises, alternate qualified routes, shared bottleneck stations, and program-level ripple traces across complex routings.

  • Order-level ATP/CTP
  • Alternate machine routing
  • Program milestone tracking
Explore Aerospace
Vertical

Process manufacturing

Campaign windows, min/max batch sizes, shared reactors, and material readiness gates — DES models the queue effects process planners actually fight.

  • Campaign scheduling
  • Resource pool contention
  • Process route alternates
Explore Process
Vertical

Discrete manufacturing

CNC job shops, custom lots, shared stations, and order-level promises — with per-commitment slip attribution when one machine goes down.

  • Factory line designer
  • Chaos mode stress tests
  • Actuals → auto replan
Explore Discrete
Vertical

Medical devices & life sciences

Traceable schedules from PO to operation, CAPA-style pre-commit preview, and deterministic scenario replay for quality and regulatory review.

  • Pegging tree export
  • Role-aware change preview
  • Shop-floor calibration loop
Explore Medical

Your ERP tells you what happened. RippleFlo tells you what will happen on the shop floor.

Discrete-event simulation for critical manufacturing — model machines, queues, operators, shifts, failures, and WIP, then run virtual production days before changing a single setting on the real line.

ERP / MES

System of record

ERP plans, schedules, and accounts for what actually happens. It's transactional — orders, BOMs, inventory, work-orders, costs.

  • Answers: what did we produce, ship, and consume?
  • Static plans built on average lead times
  • Cannot model machine failures, queues, or variability
  • Changing a parameter means changing the real plant
RippleFlo

System of foresight

A discrete-event digital twin of your line. Time advances event by event: an entity arrives, a machine seizes a resource, a failure occurs, a shift ends. You watch the factory run — virtually.

  • Answers: what will happen if we change X?
  • Stochastic — handles variability, breakdowns, and repair times
  • Models WIP, buffers, operators, shifts, and scheduling rules
  • Runs thousands of replications in minutes — zero shop-floor risk

Same factory. Two very different questions.

DimensionERP / MESRippleFlo
Time modelCalendar / batchEvent-by-event (discrete)
PurposeExecute & recordPredict & decide
VariabilityAverages onlyDistributions & randomness
Failures & repairsLogged after the factModelled as first-class events
Scenario costReal production changeA re-run of the model
Queue & contentionHidden in averagesQueues, blocking, starvation visible
OutputReports & invoicesThroughput, utilisation, WIP, bottlenecks, ripple traces
Schedule changesPublish and hopePre-commit blast preview before you publish

Problems that only simulation can solve.

ERP keeps the lights on. RippleFlo tells you where to point them next — with numbers, not gut feel.

Bottlenecks stay invisible

ERP averages utilisation across a week. It won't show that Mill is at 96% while Cut starves 14% of the time.

Failures are history, not forecasts

A breakdown is logged after production stops. ERP can't inject MTBF/MTTR and ask: how many orders slip if CNC1 is down 600 minutes?

Buffers are guesses

Right-sizing WIP between stations requires simulation — ERP has no queue model to run the buffer-allocation problem.

What-if costs the floor

Testing a new shift pattern, staffing level, or capex decision in ERP means changing live settings. RippleFlo runs it virtually first.

From model to insight in five steps.

01
Describe
Sources, machines, queues, exits — your line digitally twinned.
02
Connect
Wire routings, alternates, and resource pools into a graph.
03
Parameterise
Processing times, failures, shifts, calendars, scheduling rules.
04
Replicate
Run stochastic replications in Simulation Lab — 1 to 20 per scenario.
05
Decide
Read throughput, utilisation, WIP, ripple traces — then publish with evidence.

Decisions you can defend with numbers.

Find the real bottleneck

Utilisation per station, queue lengths, and starvation ratios expose the constraint your ERP averages away.

Right-size buffers & WIP

Sweep buffer configurations across thousands of replications and pick the throughput-per-inventory winner.

Stress-test failures & repair

Inject realistic MTBF/MTTR. Decide repair capacity before signing a contract — not after a crisis.

Validate shifts & staffing

Compare 2-shift vs 3-shift, end-of-shift rules, and operator allocation with measurable off-shift impact.

Compare scheduling rules

Rank dispatching policies by tardiness, flow time, and WIP in a job-shop — before the floor adopts one.

De-risk capex

Prove throughput and ROI in the model before buying a new line. The cheapest experiment is the one you don't run on the plant.

Stop guessing. Start simulating.

Bring decisions — not opinions — to the next ops review. Model your line, run the scenarios, and trace every ripple before it hits production.

See RippleFlo vs your ERP

One operating system for production planning.

Design → Plan → Simulate → Schedule → Actuals → Replan. Critical manufacturing, process campaigns, and discrete lines in one closed loop.

01

Model the real factory

Lines, routings, calendars, alternates — your shop floor, digitally twinned.

02

Simulate forward with DES

Event-driven engine captures queues, blocking, and variability.

03

Inject discrete events

Breakdowns, material delays, demand surges — measure commitment impact.

04

Close the loop with actuals

Shop-floor timings calibrate your model and trigger automatic replan.

600 minutes on CNC1. Three lots, three different stories.

Naive schedulers say “later = worse.” RippleFlo measures slip per order against its own plan — so Lot 2/6 finishes 4 hours late while Lot 3/6 only slips 40 minutes because its downstream path took an alternate route.

  • Per-commitment slip with attribution (% CNC1 vs downstream queue).
  • Stage-to-stage trace: if CNC1 slips, when does Final QC move?
  • Pre-commit blast preview — before you publish, see who gets hit.
Ripple impact · CNC1 downtime
600 min
Lot 1/6
+0 min
Lot 2/6
+4h 12m
Lot 3/6
+40 min
Lot 4/6
+2h 05m
Lot 5/6
+5h 30m
Lot 6/6
+1h 10m

Engineered for critical manufacturing — where every slip has stakes.

Pharma, aerospace, medical devices, defense, process, and regulated discrete. Environments where every minute is traceable, every change is reviewed, and every customer commitment is contractual. RippleFlo brings the rigor.

100%
of schedule changes captured in audit log
0
spreadsheet-driven late-discovery surprises
Minutes
to reproduce any historical scenario
01

Audit-grade traceability

Every schedule decision, simulation run, and replan is archived. Export the pegging tree from commitment back to root cause for internal review or regulator.

02

Validate before you commit

Pre-commit blast preview shows exactly which lots, batches, and customer promises shift — before a single change touches the floor.

03

Release & commitment risk scoring

Risk analytics flag equipment conflicts, calendar collisions, and CAPA-style actions before they become deviations — for batches, orders, and programs.

04

Deterministic replay

Re-run any historical scenario with identical inputs. Reproduce, review, and defend every scheduling decision you ever made.

05

Earlier-than-human warning

Amber and red alerts fire days before a slip becomes a missed commitment — giving QA, planning, and customer success room to act.

06

Alternate-route resilience

When a qualified machine goes down, DES finds the next compliant route automatically — respecting validated equipment trains.

Defensible schedules. Reviewable decisions. Repeatable outcomes.

Simulation History preserves every run with station metrics, event traces, and CSV exports. Commitment Diff captures what changed and why. Recipe calibration links shop-floor reality back to your planning model — closing the loop your quality team already expects.

  • Pegging tree from customer order → lot → batch → operation
  • Full simulation archive with replay and export
  • Commitment Diff for every schedule publication
  • Role-aware change preview before publishing
Talk to a critical-manufacturing engineer
pegging.trace · LOT-2208-B
PO #48201 · Customer ACME-Bio
└─ Batch BX-77 · Release Sep 14
└─ Lot 2208-B · 4h slip
└─ Op 040 · CNC1 down 600m
└─ Reroute → CNC3 (validated)
└─ Audit entry #91244 ✓
Sign-off
QA · Planning · Ops
Replay
Deterministic ✓

Watch your line breathe — every unit, every station, every slip.

Design dual-flow lines, route through alternate equipment, and see the discrete event simulation stream units between stations in real time. Bottlenecks light up the moment they form.

Production Line 1· DES tick 00:14:32
CNC1
1h30/u · buf 2
Processing
CNC QC
3m/u · buf 1
Processing
CNC2
2h/u · buf 18
Slow
Drilling
3m/u · buf 15
Processing
Grinding
1h/u · buf 6
Delayed
Painting
15m/u · buf 6
Processing
Furnace
30m/u · buf 4
Idle
Final QC
3m/u · buf 20
Processing
Packaging
4m/u · buf 12
Released
Ripple Alert
CNC2 running slow
Grinding queue +12 min · Lot 4/6 at risk
Throughput
42 u/h
vs 45 target
WIP
118
+6 vs plan
OEE
78.4%
+1.2
On-time proj
94.2%
+6.1 vs base

Six modules. One closed loop.

Design

Factory & Line Design

Top-down layouts, drag-and-drop stations, primary/secondary/bypass routes. Per-station cycle times, distributions, MTBF/MTTR, resource pools.

Plan

Production Planning

Order and batch entry with ATP/CTP feasibility, calendar-aware ideal/ASAP/Start-now options, lot splitting, campaign windows, and material readiness gates.

Simulate

DES Scheduling Engine

ManPy-inspired event engine: Source → Machines → Queues → Exit. Captures waiting, blocking, starvation that Gantt tools miss.

Stress

Discrete Event Chaos Testing

Inject breakdowns, material delays, worker absence, rework, demand surges. Test it in software before the shop floor finds out.

Trace

Ripple Observability

Trace a delay from source through every downstream stage. Per-commitment severity. Stage-to-stage what-if queries.

Loop

Actuals → Calibration → Replan

Capture shop-floor timings, recalibrate recipes, and auto-replan remaining steps from actual finish time.

Platform advantages that apply everywhere.

The same DES core powers critical manufacturing rigor, pharma batch planning, aerospace programs, and CNC job shops.

01

DES engine, not static Gantt

Event-driven simulation captures queues, blocking, and starvation that spreadsheets and ERP schedulers miss — across discrete, process, and hybrid lines.

02

Ripple observability

Trace any delay from source station through every downstream stage. Per-commitment severity with station-level attribution.

03

Critical mfg traceability

Simulation history, commitment diff, and deterministic replay — the evidence layer regulated and high-stakes environments require.

04

Chaos testing before the floor

Inject breakdowns, material delays, demand surges, and rework. Measure impact in software before the shop floor or QA finds out.

05

Closed-loop calibration

Shop-floor actuals recalibrate recipes and trigger automatic replan — keeping your digital twin aligned with reality.

06

Alternate-route resilience

When primary equipment is down, DES finds the next compliant path — qualified alternates for aerospace, pharma, and discrete alike.

07

Calendar-aware planning

Shifts, holidays, maintenance windows, and equipment calendars baked into every feasibility check and simulation run.

08

Earlier-than-human alerts

Amber and red warnings fire days before a slip becomes a missed commitment — orders, batches, programs, and release windows.

Spreadsheets pretend. DES proves.

RippleFlo simulates your factory as a sequence of events — jobs arriving, machines starting, breakdowns happening, repairs finishing. It captures the queueing, blocking, and starvation that static Gantt tools can’t see.

Spreadsheet / static GanttRippleFlo DES
Assumes fixed durationsModels queues & contention
One delay = manual fixRipples propagate automatically
Ignores shifts and holidaysFactory calendar aware
Hard to compare scenariosBaseline vs scenario side-by-side
No audit trailSimulation history archive
Discrete event simulation timeline
Monte Carlo
1 – 20 runs
per scenario in Simulation Lab
Recipe routing
+ Alternates
when primary is unavailable

Don’t discover the ripple on the floor. Inject it in software first.

Machine breakdown
station · duration · start
Material delay
SKU or order-specific
Quality reject / rework
quantity multiplier
Demand surge
+25%, +50%, custom
Scenario
CNC1 down · 600 min · Tuesday 06:00
+3
Late orders
2h 41m
Avg slip
88%
On-time
Compare against baselineOpen in War Room
Ripple propagation map across station nodes
Crisis level
Amber

From source station to customer commitment in one trace.

See exactly how a delay propagates. Severity scoring (on track / at risk / late / critical) per commitment. Attribution per station. Open the War Room for crisis-level coordination with pre-commit blast preview.

Per-commitment severity
On track · At risk · Late · Critical
Station attribution
% from source vs downstream queue
Pre-commit blast preview
See who gets hit before publishing
Replan Assistant
Overtime, alt route, split, defer

Plan once. Calibrate continuously.

Plan
DES schedule
Execute
Actuals captured
Measure
Variance reports
Calibrate
Recipe tuning
Replan
Auto reschedule

How DES saves time and money.

Before and after, across the moments planners actually feel pain.

Pain
Without RippleFlo
With RippleFlo
New order promise date
Guess from average lead time
Feasibility simulation with calendar
Machine down
Phone tree, manual reschedule
War Room + ripple trace in minutes
Late discovery
Customer or QA finds it late
Amber/red alerts days earlier
Batch / campaign change
Manual re-plan across teams
One ripple trace end-to-end
Planner vs floor mismatch
Spreadsheet drift
Actuals on timeline + auto replan
Capital investment
Buy another machine?
DES proves the bottleneck first
Regulatory / audit review
Reconstruct decisions manually
Deterministic replay + audit archive
Scenario comparison
Meetings
Simulation Lab · 5–20 replications
30%↓
schedule rework hours
10×
faster what-if cycles
Days
earlier late-order warning

Typical results observed with early RippleFlo customers. Your mileage will vary.

See your factory simulated in 30 minutes.

Load a sample scenario — CNC Dual-Flow, 100 orders, pharma batch line, or aerospace routing — and walk through a real ripple trace with our team.